Register for free to
view the full innovation profile.
Palm fruit juice (PFJ) is a cost-effective source of dietary phenolics including cinnamate and benzoate derivatives which prevents diabetes and reduces lipid levels.
About
Background: Numerous studies have suggested regular consumption of plant-derived bioactive phytochemicals may be able to delay or prevent the onset of serious cardiovascular and metabolic diseases through their anti-inflammatory and antioxidant effects. Palm fruit juice (PFJ), the water-soluble by-product after oil extraction from the fruit during the milling process, is surprisingly a natural source rich in phytochemicals, in particular, bioactive phenolic compounds (“oil palm phenolics” or OPP). Our invention is the use of OPP from PFJ as prophylactic or therapeutic dietary supplements in humans and animals. We have discovered OPP possesses anti-hyperglycemic and antihyperlipidemic properties when provided in the regular diets of animals genetically prone to developing type II diabetes.1 Following 12-weeks of consumption, diets supplemented with PFJ lowered fasting blood glucose levels ~5.4 fold in older diabetic animals (i.e. 650 mg/dL vs. 120 mg/dL) and resulted in overall levels near those of their non-diabetic controls fed either water or PFJ (i.e.
Key Benefits
Green technology generated as a by-product of palm oil production - the world’s No. 1 edible oil Abundant, low-cost sourcing by concentrating OPP from water waste created during oil milling Versatile nutraceutical/pharmaceutical delivery options in pill, powder, gel, or liquid formulations
Applications
In the prevention and treatment of diabetes mellitus (type 1, type 1.5, and type 2), gestational diabetes, genetic defects of β-cell function or insulin action, pre-diabetes, and metabolic syndrome.