Thermoelectric Sensor

About

About Changes in temperature can be a good way to measure a chemical or biological activity, providing both real-time (kinetic) or end-point (steady-state) information. There are numerous examples of the use of this method, termed calorimetry, in use throughout analytical sciences and biotechnology. There are a number of reactions where very small amounts of heat are produced (or consumed). This might be because the sample is very small, or because the reaction itself does not result in a large energy change. The Thermoelectric Sensor technology is a Nano-Calorimetric Sensor which measures very small changes in temperature. The IP provides a route to making the most sensitive calorimetric measurements (with a resolution of (0.1 mK). It is also ideally suited to analysis of small samples, associated with Lab-on-a-Chip methods.   Key Benefits Faster assays allowing real-time measurements of thermal changes in biological samples  96 well high throughput format compatible with existing HTS equipment – higher multiples 384, 864 and 1536 plate formats may also be used  Application with a wide range of biological samples including single cells, small groups of cells, tissue samples, cell-free extracts , cell organelles or isolated biochemical materials such as enzymes or components of biochemical pathways  Easy manufacture using known methods adapted from the semiconductor industry   Applications Array Formats for High throughput drug discovery/Compound Analysis  Measurement of Drug Interactions with Proteins, Ligands or Receptors  Protein Crystallisation Studies  Clinical Diagnostics  Environmental Diagnostics  Gas Sensing Molecular Biology – PCR Amplification   IP Status This technology is available as an Easy Access deal, available to companies and individuals to licence for FREE.