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Axial resolution down to a few microns has been obtained in the living human retina.
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Summary Adaptive optics is used in optical coherence tomography (OCT) to provide very high axial resolution in a non-invasive "optical sectioning" technique for imaging at various depths within living human tissue. In the current commercial application of OCT for retinal imaging, the transverse resolution is limited by the intrinsic ocular aberrations of the eye. This invention applies adaptive optics via a deformable mirror and wavefront sensor to correct for those aberrations.