Reconstruction of hollow organ

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Stanford Reference: 15-163 Abstract Researchers at Stanford University have developed an algorithm for 3D reconstruction and co-registration of endoscopic video that is easily translatable to clinical use (i.e., using standard clinical equipment). The current standard of care to diagnose and manage epithelial cancers, such as bladder, colon and esophageal cancers, is by imaging with white light endoscopy. The data collected from the procedure is usually condensed into a few still images, clinical notes and diagrams; interpretation can be subjective. The video data from the procedure is rarely captured or reviewed; however, methods that can recast video captured during endoscopy into a simpler, more intuitive and viewer-friendly format would be beneficial as they may allow easier, less subjective longitudinal monitoring. To help meet this need the inventors developed this technology. It enables video collected from hollow organs during white light endoscopy to be reconstructed into 3D models with the appearance of the anatomy. In addition, it allows for co-registration of reconstructions from different endoscopy sessions to allow longitudinal monitoring. These comprehensive reconstructions enable the physician to quickly visualize the locations and details of the cancerous lesions. This technology will improve clinical care as it provides visual medical records to aide perioperative management and long-term surveillance of patients. Stage of research Inventors built a prototype for collecting clinical data and demonstrating the feasibility of this approach. Applications 3D reconstruction of endoscopy video for use in: Cystoscopy Colonoscopy Upper gastrointestinal endoscopy Pulmonary endoscopy Advantages Provides a 3D reconstruction of the whole organ Has ability to zoom in and out of the mucosa of interest Allows for spatially located annotations Easily translatable to clinic: Uses standard clinical instruments such as endoscopes, light sources and camera heads Compatible with standard video recording across different platforms Output is intuitive Allows co-registration of reconstructions from different endoscopy sessions- enables comparison of the appearance of hollow organs after a procedure and over time Uses video stream rather than static images