Raman Spectroscopy

About

About this innovation Surface enhancement in RAMAN-spectroscopy has proven to greatly improve the RAMAN-signal, increasing sensitivity with several orders of magnitude. Unfortunately, until now, surface enhancement could not efficiently be integrated in most RAMAN-based sensor applications as surface enhancement technology is limited to one shot measurements due to irreversible binding of the analyte to the SERS-substrate. This makes SERS-technology not suitable for use in applications where continuous dynamic measurements are required. SERS-based sensors that can make dynamic measurements of their environment over time. Sensors like these would be ideally suited for application in, for instance, industrial process monitoring. They can continuously monitor flows of substances (in aqueous solution) for contaminations or formed substances and upon identifying such substances, measure their concentration over time. Furthermore, this new technology makes the SERS-substrates re-usable, which allows for calibration of experimental setups and greatly reduces the number of substrates required per experiment. This makes the new SERSOR very suitable for applications where many different molecules need to be analyzed. Key Benefits Compatible with standard RAMAN spectrometer Higher sensitivity of SERS measurements Continuous dynamical measurements Sensitive to broad range of anayltes No chemical interaction between sensor and analyte Small, Integratable in microfludic devices Applications In-line detectors Process monitoring Medical diagnostics In vivo monitoring Metablolomics and other -omics