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UC Berkeley researchers have developed hydrogel cell matrices for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making cells.
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Brief Description: The encapsulation of stem cells in a hydrogel substrate provides a promising future in biomedical applications. However, communications between hydrogels and stem cells is complicated, for example, factors such as porosity, different polymer types, stiffness, compatibility and degradation will lead to stem cell survival or death. Hydrogels mimic the three-dimensional extracellular matrix to provide a friendly environment for stem cells. UC Berkeley researchers have developed hydrogel cell matrices for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making such hydrogel cell matrices. Suggested Uses: Cardiac tissue engineering Reinforcement of scleral tissue Fat tissue engineering Wound healing matrix Drug delivery Advantages: Increases survival and engraftment of transplanted stem cells Hydrogel has tuneable release kinetics and degradation rate