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Novel Microbial Control Approach via Molecular roadblocks for RpoN binding sites
About
An engineered peptide represses expression of various bacterial genes controlled by the global regulator RpoN, thus shutting down many metabolic pathways that bacteria need for growth, infection, and virulence. The method can be used to inhibit bacterial motility, growth, quorum sensing, attachment, virulence, and biofilm formation. Patents: U.S. 9,392,790; 9,879,051 SUNY-ESF-1816
Key Benefits
(1) Bio-control capabilities. (2) Low risk of resistance. (3) Broad spectrum.
Applications
Antimicrobial infection control.