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The invention related to hybridoma cell lines producing monoclonal antibodies to DNA, which were generated from autoimmune (NZB x NZW) F1 mice.
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Description: The invention related to hybridoma cell lines producing monoclonal antibodies to DNA, which were generated from autoimmune (NZB x NZW) F1 mice. The specificities of the monoclonal antibodies range from low avidity, ssDNA-binding antibodies to high avidity, ssDNA and dsDNA binding antibodies.