Injectable Gel from Proteins

About

Value Proposition For patients suffering from peripheral nerve injury and the clinicians who serve them, NeuroGel is a flexible, easy to use gel that promotes nerve regeneration and restoration of function. Where surgery currently provides less than satisfactory recovery of function and current nerve guides can only be used in limited situations, NeuroGel provides a solution that is uniquely versatile and better able to promote nerve regrowth and functional regeneration. Market Opportunity Almost a million surgeries occur every year to repair nerve injuries of the extremities. The costs of these procedures add up to $1.68 B annually, but the total associated cost of care approaches $7 B in US every year. Based on interviews with clinicians, we have identified a need for a product that would improve recovery after surgical repair of nerves that does not exists today and NeuroGel is uniquely qualified to fill this gap in the market. Competitive Landscape Nerve injury exists on a spectrum from mild to severe involving a range of injury types from compression, severing, and gap, respectively. The injectable nature of NeuroGel allows for use in multiple contexts, including all three basic injury types. This provides a distinct advantage for NeuroGel. While competition exists in the nerve gap market, very little exists on the market to assist in the repair of severed or compressed nerves. In addition, the major competition in the market of repair of severed nerves, AxoGuard has only gained a fraction of a percent of the total market after 11 years on the market. Technology NeuroGel is an injectable gel that is made from the proteins and growth factors contained in nerves. While, similar protein or extracellular matrix scaffolds have been used to treat over a million patients in other applications successfully, NeuroGel is the only product using nerve specific components for nerve repair. We have shown in several pre-clinical animal studies that NeuroGel promotes nerve regrowth so that patients can regain function sooner.