Hemorrhagic Stroke Treatment

About

BACKGROUND Stroke is a leading cause of death and adult disability in the world. The second most prevalent type of stroke, known both as intracerebral hemorrhage (ICH) and hemorrhagic stroke (HS) has the poorest prognosis of all stroke subtypes and is responsible for about 40 percent of all stroke deaths.  However, there are currently no drugs available to treat ICH, as the mechanisms behind the brain damage caused by ICH have been only partially understood. TECHNOLOGY DESCRIPTION Researchers at the University of New Mexico have been studying mechanisms of brain damage in ICH/HS and have some important discoveries regarding the molecular process of ICH/HS-induced brain injury. Consequently, they have identified novel small molecules to prevent brain tissue damage. These molecules show benefits using both in vitro and in vivo ICH/HS models offering a new potential approach for reducing brain damage.  ADVANTAGES/APPLICATIONS New potential target for reducing brain damage following intracerebral hemorrhage.