Health-promoting supplement

About

Gut inflammatory bowel diseases (IBDs) are costly and serious diseases in childhood development. New natural microalgae-based supplement that promote gut health and control IBDs has been produced. The products, AggieFeed and AggieGrow can be manufactured in large quantity using all natural ingredients, and show no cytotoxicity or adverse health effects in cell-based and animal studies.. Preliminary results with mice demonstrate the cytoprotective effects of AggieFeed-supplemented animal feed for alleviating IBD. Addition of AggieFeed in regular feed reduces the levels of inflammatory cytokines IL-6 and TNF-α, and pro-inflammatory cytokine IFN-alpha while exerts no immunogenic response. More evidence has shown that AggieFeed supplementation promotes the growth of chicken, piglets and trout, and improves gut health and gut microbiome profile without antibiotic addition. Additional information is listed: Ito,T.; Chen, D; Chang, C.-W. T.; Kenmochi, T.; Saito, T.; Suzuki, S.; Takemoto, J. Y. "Mesobiliverdin-IXa Enhances Rat Pancreatic Islet Yield and Function." Frontiers in Drug Metabolism and Transport, 2013, 4, 1-8. PubMed PMID: 23630498; PubMed Central PMCID: PMC3633165. Chang, C.-W. T.; Takemoto, J. Y.; Chang, P.-E.; AlFindee, M. N.; Li, Y.-Y. “Effects of Mesobiliverdin IXa-Enriched Microalgae Feed on Gut Health and Microbiota of Broilers.” Frontiers in Veterinary Science, January 2021, volume 7, article 586813. https://pubmed.ncbi.nlm.nih.gov/33553275/ Lin, Y.-Y.; Takemoto, J. Y.; Chang, C.-W. T.; Peng, C.-A. “Mesobiliverdin IXα ameliorates osteoporosis via promoting osteogenic differentiation of mesenchymal stem cells.” Biochem. Biophys. Res. Commun. 2022, 619, 56-61. https://doi.org/10.1016/j.bbrc.2022.06.042. More information has not been published but can be available with contact of the inventors.