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MicroFFE Chip prototype able to sustain prolonged, complete and steady continuous separation of chemicals,as well as proteins for several days.
About
An innovative microFFE chip mainly composed of a fluidic circuit designed in a film clamped between two plates of glass has been developed to get rid of these different drawbacks and can purify/separate chemicals as well as proteins with excellent resolution and long-term stability of the flow, enabling continuous process. This new microFFE solution is, therefore, a great opportunity to fulfill the unmet need for purification/separation of sensitive material such as cells, liposomes, exosomes, etc. The “matrix-free” aspect of this system is also a highly valuable cost-effective advantage (reduced OPEX) compared to other separation/purification solutions. Moreover, the possibility of chip numbering-up avoids scale-up issues of the solution, making it perfectly suitable for
large-scale production capacities. Finally, this microFFE solution enables the purification and
concentration of the compound of interest in a single step, leading to simplification of the downstream bioproduction processes.
Key Benefits
Simplified process development
• One technology
• No membrane or media choice
• No scaling-up
Easier processing of difficult/sensible products
Oversimplified quality management
• No material aging
• No intermediate storage
OPEX reduced cost
Applications
Separation of chemicals, as well as proteins