The kit allows for distinguising between RhD positive, negative and RhD PSI genotypes.

About

Description: The RhD Fetal Blood Genotyping kit targets sequences specific for exons 5, 7 and 10 of the RhD gene and can distinguish between RhD positive, negative and RhD PSI genotypes in cell free fetal DNA and in a background of maternal cell free DNA. A control gene (CCR5) is also included to confirm adequate cell free DNA quantity within the sample. Technical Performance:  Technical sensitivity of the assay was demonstrated (figure 1) on artificially prepared genomic DNA samples containing RhD negative DNA spiked with 1 or 10% (equivalent to 3 or 30 genomic equivalents) RhD positive DNA. Samples containing only RhD positive or negative genomic DNA were also included as controls.  

Register for free for full unlimited access to all innovation profiles on LEO

  • Discover articles from some of the world’s brightest minds, or share your thoughts and add one yourself
  • Connect with like-minded individuals and forge valuable relationships and collaboration partners
  • Innovate together, promote your expertise, or showcase your innovations