Emulsion Templated Foam

About

  Overview This technology is the emulsion-templated foam material that enables further disclosures (TEES3842 & TEES3849) to repair and provide treatment to damaged tissue. Technology An emulsion-templated foam of high porosity and increased modulus and strength, in particular when compared to current gel-based, injectable systems. Further, this process enables the co-delivery of other medications (such as mesenchymal stem cells) with drastically reduced dispersion rates to non-defective areas. Advantages Co-delivery creates potential for greatly improved healing and recovery speed Can fill irregularly shaped defects Improved contact between scaffold and surrounding tissue No need for (costly) molding techniques Applications Tissue repair and regeneration Regularly and irregularly shaped damage / defects Critical-sized trauma, congenital, tumor, etc. defects or deformities In vivo, in situ cure for tissue grafting Stage of Development Developed laboratory prototypes, but no testing Patent Status Patent Issued: 9,180,094 Publications E. Cosgriff-Hernandez, et al. “Injectable, High Porosity Bone Grafts by Emulsion Templating.” TISSUE ENGINEERING PART A. Vol. 21., 2015. P. Singhal, E. Cosgriff-Hernandez, D. J. Maitland and T. S. Wilson. “Low density biodegradable shape memory polyurethane foams for aneurysm treatment,” Acta Biomaterialia, in press (2013). R. Moglia, J. Holm, A. Muschenborn, T. Touchet, D. Maitland, E. Cosgriff-Hernandez, “Injectable and porous polyMIPE scaffolds for soft tissue regeneration,” Polymer, in press (2013).