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By ensuring the proper distribution of fatty acids many conditions can be treated such as different types of cancer or neurological disorders.
About
Background: A ketogenic diet (KD) is a low carbohydrate high-fat diet that was designed originally to manage seizures in children with epilepsy. The KD mimics the physiological state of fasting, which was known since the time of Hippocrates to reduce seizure susceptibility. An energy transition from carbohydrate metabolism to fat metabolism is thought to contribute to the therapeutic benefits of KDs. As with therapeutic fasting and calorie restriction, it remains unclear if the anti-epileptic and anti-convulsant effects of the KD are due to reduced glucose, to elevated ketone bodies, or to some combination of these effects. The present invention involves a novel fatty acid composition for the therapeutic success of KDs. Invention: The invention provides the distribution of fatty acids in the KetoGen ketogenic diet. This diet has powerful therapeutic effects against tumor growth, brain tumor invasion and systemic metastatic cancer in the VM-M3 mouse model of invasive/metastatic cancer. The therapeutic effect of the KetoGen ketogenic diet is significantly better in reducing primary tumor growth and systemic metastasis in the VM-M3 mouse model than other ketogenic diets in the market. The invention has potential indications: for all types of cancer, neurological disorders, and chronic inflammatory diseases. Features/Advantages: • Novel KetoGen fatty acid formulation is more therapeutically effective than other ketogenic diet fatty acid formulations currently in the market • KetoGen KD can be an alternative non-toxic dietary therapy to control tumor growth, invasion and metastasis Applications: This novel therapeutic fatty acid composition could be used for managing: Cancer (including brain, breast, lung), neurological disorders, and chronic inflammatory diseases Lead Inventor: Thomas N. Seyfried, Professor, Department of Biology, Boston College Patent Information: U.S. Patent Application has been filed Licensing Status: Available for exclusive or non-exclusive license Looking for Partners: For sponsored collaboration research to develop and commercialize this invention