Chromatography

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Summary The technology creates a new stationary phase that separates compounds based upon their interaction with water. Water-active species are "problem" species in organic matrices because they are often responsible for emulsion formation/stabilization in chromatography. This technology provides an easy and quick way to isolate water-active species that currently does not exist. The technology has already been applied to separate interfacially active species from petroleum crude oils/organic matrices. Benefits Most stationary phases in chromatography are based upon silica, alumina, or polymers to allow for the retention of compounds. However, no current commercially available stationary phase is based upon the interaction of compounds with water, because water has not been immobilized as a stationary phase. Immobilized water on silica gel creates a consistent product that can be reproduced. Since the stationary phase is created at room temperature (22-25°C), there are no difficulties with creation, storage, and usage of the stationary phase. The stationary phase has a long shelf-life (4+ years) and could be produced in bulk and stored until use, thus making it desirable for commercialization.