Register for free to
view the full innovation profile.
Novel process to microfabricate perfectly spherical concave lab-on-a-chip bioreactors that can be used capture cells from steady flow and maintain them for basic research.
About
Brief Description: A lab-on-chip bioreactor for cell capture and analysis. Applications: This invention describes a novel process to microfabricate perfectly spherical concave lab-on-a-chip bioreactors that can be used capture cells from steady flow and maintain them for basic research investigations and/or for use in medical diagnostics/treatment. One application has been to capture stem cells from peripheral blood and maintain them in the bubble bioreactors for further investigation. Advantages: Computational fluid dynamics (CFD) analysis indicates that these spherical bioreactors have unique flow properties that are sufficient to maintain viability of cells.