Bioactive Avian Interleukin

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Project Summary Arkansas State University and BioStrategies LLC are developing a patented method for production of bioactive avian IL-12 in plants. The technology provides commercially applicable yields of plant-produced bioactive avian IL-12 at levels of at least 1% total soluble protein. Bioactive avian IL-12 protein synthesized in a plant successfully functions in vitro and in vivo as a potent immune modulator and an adjuvant that significantly enhances the efficacy of veterinary vaccines against avian influenza and other poultry diseases. The compound is proven to elicit protective and immune response in birds. Applications  Veterinary vaccine production specifically for poultry industry, including, but not limited to chicken and turkey. Research reagent supplies for immunological studies and vaccine development and testing. Probiotic feed supplements for poultry, which can be used as an alternative for antibiotics to promote growth and protection from disease by enhancing immune system.