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The present invention relates to novel derivatives of the antimalarial artemisinin, methods and compositions for their preparation, and their uses in pharmaceutical compositions.
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Brief Description: The present invention relates to novel derivatives of the antimalarial artemisinin, methods and compositions for their preparation, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections (primarily malaria). Advantages: Despite their viability of semisynthetic artemisinin as antimalarial agents, an important drawback is its very short half-life in plasma and in the human body(